What is baclofen and how to use it?
What is baclofen?
Baclofen is a muscle relaxer and an antispasmodic agent.
Baclofen is used to treat muscle pain, spasms, and stiffness in people with multiple sclerosis or spinal cord injury or disease.
Baclofen is given intrathecally (directly into the spinal cord) or orally (by mouth).
Name: Baclofen
Alias: chloramphenicol butyric acid
Chemical formula: C10H12ClNO2
Molecular weight: 213.661
CAS Registration: 1134-47-0
EINE:214-486-9
Melting point: 208 to 210 ℃
How should I take baclofen?
Take baclofen exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
Shake the oral suspension (liquid) before you measure a dose. Use the dosing syringe provided, or use a medicine dose-measuring device (not a kitchen spoon).
Call your doctor if your muscle symptoms do not improve, or if they get worse.
You should not stop using baclofen suddenly or you could have serious or fatal withdrawal symptoms. Follow your doctor's instructions about tapering your dose.
Indications:
1. Used for skeletal muscle spasms caused by multiple sclerosis.
2. Used for spastic states caused by infectious, degenerative, traumatic, tumor, or unexplained spinal cord diseases, such as spastic spinal cord palsy, amyotrophic lateral sclerosis, syringomyelia, transverse myelitis, traumatic paraplegia or paralysis, spinal cord compression, spinal cord tumors, and motor neuron disease.
3. Used for cerebral muscle spasms, such as those caused by cerebral palsy, pediatric cerebral palsy, stroke, cerebrovascular accidents, brain tumors, degenerative encephalopathy, meningitis, and craniocerebral trauma.
4. It can also be used for urinary retention caused by spasm of external sphincter.
Usage and dosage:
Oral administration: Start with 5 mg/time, 3 times/day, and increase the dose every 3 days, each time increasing by 5 mg, until the required dose is reached. Generally, the appropriate dose is 75 mg/day, and can reach 100 to 120 mg per day depending on the condition. Children typically receive 4 doses per day, with a recommended maintenance dose of 10-20 mg/day from 12 months to 2 years of age; Children aged 2-6 years: 20-30 mg. Children aged 6-10 years: 30-60 mg (maximum 70 mg).
